Tracid Injection 500mg/5ml

✔️ Indications: Tranexamic Acid

• In Medicine: Prophylaxis and treatment of hemoptysis, digestive hemorrhages, hemorrhagic syndromes in leukemia, cirrhosis, hemophilia, thrombocytopenic purpura, accidents during thrombolytic therapy, and transfusion.
• In Surgery: Prophylaxis and anti-hemorrhagic therapy during various surgeries, especially pulmonary, cardiovascular, and abdominal surgeries, as well as post-operative and traumatic shock.
• In Urology: Prophylaxis and anti-hemorrhagic therapy for prostatic, vesical, and renal surgery; hematurias.
• In Obstetrics: Prophylaxis and therapy for post-partum and puerperal hemorrhages, hemorrhagic enteropathies, menometrorrhagia (including IUD-induced), and hyperfibrinolysis (e.g., abruptio placentae, premature placenta detachment).
• In Otorhinolaryngology: Prophylaxis and anti-hemorrhagic therapy during tonsillectomy and specialist surgeries, and for epistaxis.
• In Stomatology: Prophylaxis and anti-hemorrhagic therapy during maxillofacial operations and tooth extractions.
• In Oncology: To promote fibrin capsule formation around ovarian tumors, reduce ascites in carcinoma, and reduce bleeding during surgery.

✔️ Side Effects

Generally well-tolerated; rare effects include fatigue, conjunctival irritation, nasal blockage, itching, skin reddening, exanthems, nausea, diarrhea, gastric pyrosis, and postural hypotension.

✔️ Some Suggestions:

• Stay hydrated and consume plenty of fluids. Fluids are necessary to maintain blood flow in your body.
• Consume fresh fruits and vegetables. Consult a dietitian and prepare a diet plan. Eating healthy can help you to recover faster.
• Your doctor may suggest regular eye check-ups while taking Tranexamic Acid.
• Increased risk of blood clot formation when co-administered with a combination oral contraceptive. Consult your doctor before taking any medication.

✔️ Dosage & Administration

• Adults: 500-1000 mg, 3 times daily. For prophylaxis, 500 mg by the parenteral route. For hemorrhagic manifestations, oral doses can increase to 1-3 gm, with IV administration in urgent cases.
• Children: The prophylactic dose is 5-10 mg/kg body weight, and the therapeutic dose is 10-20 mg/kg. IV treatment may begin at 10 mg/kg.
• Elderly: No dosage reduction unless renal failure is evident.

✔️ Interaction

• Incompatible with penicillins (e.g., Benzylpenicillin).
• Antagonized by thrombolytic drugs (e.g., Streptokinase, Urokinase).
• May increase thrombus formation when used with estrogen-containing drugs (e.g., oral contraceptives).
• Avoid admixture with whole blood during transfusions.

✔️ Contraindications

• Known hypersensitivity to tranexamic acid.
• Thromboembolic disease, arterial and venous thrombosis, endocavitary hemorrhages, serious kidney failure.

✔️ Pregnancy & Lactation

• Should not be used during pregnancy due to unknown effects on the fetus.
• Passes into breast milk, but is unlikely to cause an antifibrinolytic effect in the infant.

✔️ Precautions & Warnings

• Use in hyperfibrinolysis, with prophylactic treatment beginning 24 hours before surgery and continuing 3-4 days post-operation.
• Prolong treatment for at least 24 hours after hemorrhage stops.
• Caution in renal insufficiency and anuric conditions.
• Use carefully in patients with heart or liver conditions.

✔️ Storage:

Store in a dry place at 15-30°C, away from light, and keep out of children's reach.